Why doesn't anyone understad what NO means?

Why?

Why when ones expression to a question is the word NO, does another person feel the need to check as to why? Is me saying NO not good enough? Why does it require an explanation? If I say NO does it mean “Hey I want you to ask me why I am having a difference of opinion with you right now,” or that I have no sense of self being and I need your help? WTF? Do you think me being thirty years old I need someone to ask me if I am sure?

I am tired of telling people NO and not being respected!

For example,

Do you want to try these psychotropic medications that I stole from one of my mental patients…? I reply NO, and NO THANK YOU. This individual felt it necessary to challenge my NO response with, “OHHH come on, don’t be that way it just makes you feel better.” Better than what??? I was unaware that I was feeling the wrong way. Thank you for the enlightenment.
Why would that require any further explanation other than me arresting this person for being psychotic and absolutely stupid themselves? I believe in being firm but respectful if at all possible, but other possible responses would be, “Why don’t you go outside and play hide and go fuck yourself,” or “Why don’t you pour yourself a nice hot cup of shut the fuck up and get away from me.”

Another example,

Would you like to super/biggie size that? Response is NO. Yet again to challenge my NO response,” But sir for only 39 cents more you get twice the drink and fries.”

Yet my response again is,” NO Javier’, I want only the regular sized meal, but thank you for trying to add to my problem of arterial blockage due to high cholesterol and saturated fats.”

Yet another example,

This pertains to the fine co-workers that have assumed the position as counselors, (unlicensed of course).
Say you are just having a bad day and this person (call him/her JOE/Joanne Schmuckatellie) feels the need to corner you right off the bat because you are not your usual self. You are not walking around and smiling, trying to further your promotional advancement opportunities and chances by forcing yourself to smile and make everyone else around you know that you are not disgruntled and you are in a great mood! Joe/Joeanne, ask you,” Is everything OK? Problems at home? Do you need to talk? You look upset, are you upset at me...NO, NO, NO, and NO. Why don’t you people just leave us manic depressives alone? Get this people…People have bad days! Doesn’t mean I need a hug from you and the last thing I want is for you to question my NO response and ask me over and over again, Are you OK? Or tell me that I need to be in a better mood, that I am making them depressed, how rude! Thank you for also telling me how I need to be. If you don’t like the way that I am acting then stay the fuck away from me! Not here for you, don’t require your seal of approval, but thanks. I would like my wife to ask me what the matter is and be concerned but not you. At least she respects my feelings enough to know to let me be for a bit so that I can be mad or upset. And yes I do appreciate a hug and a it’s going to be OK from her, not from someone I am forced to spend thirteen hours a day with following me around and trying to pry into my sick, twisted, angry little mind on those days!

Wheeeeew!

To sum up NO MEANS NO! Know it and respect it, I do!